High content screening identifies a role for Na+ channels in insulin production

dc.contributor.author	Szabat, Marta	en_US
dc.contributor.author	Modi, Honey	en_US
dc.contributor.author	Ramracheya, Reshma	en_US
dc.date.accessioned	2016-10-11T05:37:52Z
dc.date.available	2016-10-11T05:37:52Z
dc.date.issued	2015	en_US
dc.identifier.other	HPU4160605	en_US
dc.identifier.uri	https://lib.hpu.edu.vn/handle/123456789/23688
dc.description.abstract	Insulin production is the central feature of functionally mature and differentiated pancreaticβ-cells. Reduced insulin transcription and dedifferentiation have been implicated in type 2 diabetes, making drugs that could reverse these processes potentially useful. We have previously established ratiometric live-cell imaging tools to identify factors that increase insulin promoter activity and promote β-cell differentiation.	en_US
dc.format.extent	12 p.	en_US
dc.format.mimetype	application/pdf
dc.language.iso	en	en_US
dc.subject	Cellular andmolecular biology	en_US
dc.subject	Physiology	en_US
dc.subject	Cellular biology	en_US
dc.subject	Biotechnology	en_US
dc.subject	Islet beta-cells	en_US
dc.subject	Insulin synthesis	en_US
dc.subject	Live-cell imaging	en_US
dc.subject	Sodium channels	en_US
dc.subject	High-content screening	en_US
dc.title	High content screening identifies a role for Na+ channels in insulin production	en_US
dc.type	Article	en_US
dc.size	1.99MB	en_US
dc.department	Education	en_US