Izumo1 and Juno

dc.contributor.author	Grayson, Phil	en_US
dc.date.accessioned	2016-10-11T05:37:51Z
dc.date.available	2016-10-11T05:37:51Z
dc.date.issued	2015	en_US
dc.identifier.other	HPU4160599	en_US
dc.identifier.uri	https://lib.hpu.edu.vn/handle/123456789/23681
dc.description.abstract	Reproductive proteins are among the most rapidly evolving classes of proteins. For a subset of these, rapid evolution is driven by positive Darwinian selection despite vital, well-conserved, reproductive functions. Izumo1 is the only essential sperm–egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm–egg binding proteins are shown to be evolving under positive selection.	en_US
dc.format.extent	11 p.	en_US
dc.format.mimetype	application/pdf
dc.language.iso	en	en_US
dc.subject	Genetics	en_US
dc.subject	Evolution	en_US
dc.subject	Genomics	en_US
dc.subject	Bioinformatics	en_US
dc.subject	Izumo1 and Izumo family	en_US
dc.subject	Juno and folate receptor family	en_US
dc.subject	Reproduction and fertilization	en_US
dc.subject	Positive selection	en_US
dc.subject	Gene family evolution	en_US
dc.subject	Coevolution	en_US
dc.title	Izumo1 and Juno	en_US
dc.type	Article	en_US
dc.size	705KB	en_US
dc.department	Education	en_US