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Please use this identifier to cite or link to this item: https://lib.hpu.edu.vn/handle/123456789/23688
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dc.contributor.authorSzabat, Martaen_US
dc.contributor.authorModi, Honeyen_US
dc.contributor.authorRamracheya, Reshmaen_US
dc.date.accessioned2016-10-11T05:37:52Z
dc.date.available2016-10-11T05:37:52Z
dc.date.issued2015en_US
dc.identifier.otherHPU4160605en_US
dc.identifier.urihttps://lib.hpu.edu.vn/handle/123456789/23688-
dc.description.abstractInsulin production is the central feature of functionally mature and differentiated pancreaticβ-cells. Reduced insulin transcription and dedifferentiation have been implicated in type 2 diabetes, making drugs that could reverse these processes potentially useful. We have previously established ratiometric live-cell imaging tools to identify factors that increase insulin promoter activity and promote β-cell differentiation.en_US
dc.format.extent12 p.en_US
dc.format.mimetypeapplication/pdf-
dc.language.isoenen_US
dc.subjectCellular andmolecular biologyen_US
dc.subjectPhysiologyen_US
dc.subjectCellular biologyen_US
dc.subjectBiotechnologyen_US
dc.subjectIslet beta-cellsen_US
dc.subjectInsulin synthesisen_US
dc.subjectLive-cell imagingen_US
dc.subjectSodium channelsen_US
dc.subjectHigh-content screeningen_US
dc.titleHigh content screening identifies a role for Na+ channels in insulin productionen_US
dc.typeArticleen_US
dc.size1.99MBen_US
dc.departmentEducationen_US
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