Please use this identifier to cite or link to this item: https://lib.hpu.edu.vn/handle/123456789/22254
Title: Structures of pyruvate kinases display evolutionarily divergent allosteric strategies
Authors: Morgan, Hugh P.
Zhong, Wenhe
McNae, Iain W.
Keywords: Biochemistry
Biophysics
Structural biology
Apoenzyme
Leishmania
Trypanosoma
Issue Date: 2014
Abstract: The transition between the inactive T-state (apoenzyme) and active R-state (effector bound enzyme) of Trypanosoma cruzi pyruvate kinase (PYK) is accompanied by a symmetrical 8 rigid body rocking motion of the A- and C-domain cores in each of the four subunits, coupled with the formation of additional salt bridges across two of the four subunit interfaces.
URI: https://lib.hpu.edu.vn/handle/123456789/22254
Appears in Collections:Education

Files in This Item:
File Description SizeFormat 
0296_Structuresofpyruvatekinases.pdf
  Restricted Access
2.19 MBAdobe PDFThumbnail
View/Open Request a copy


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.